bluesav10's review against another edition

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hopeful informative fast-paced

4.75

aulimarie's review against another edition

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informative

2.0

Some of this is very informative and helpful, and I appreciated the explanation of many aspects of thyroid function. Most important for me were the parts about what vitamins and nutrients are impactful, and levels we should look for in blood tests. However I do not think her diet plan is necessary, we can all access our blood test results and work out how to get those nutrients and vitamins while eating what we want. Amy Myers is very focused on herself and how her way is the ONLY way which I think is outrageous. She is also definitely trying to sell her products throughout the book. A lot of her recommendations are also very inaccessible. Definitely need to interpret the book with a grain of salt.

swissmunicipal's review against another edition

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3.0

I generally found this to be informative and interesting - though somewhat repetitive and redundant as it proceeded. Amy Myers can have an annoying vibe at times, seemingly somewhat obsessed with herself and her own methodology- but as she has helped a lot of people with thyroid issues and much of what she talks about does appear to promote general well being.

bookishbeagle's review against another edition

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1.0

Didn’t finish the book cause doc failed to get to the point.

debralewi's review against another edition

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challenging hopeful informative medium-paced

4.0

malagajames's review against another edition

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3.0

There is lots of good information in this book, but it seems as though she is promoting her vitamins and supplements too much.

littlewit's review against another edition

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3.0

Definitely an interesting perspective and a lot to look at to figure out what's up with your thyroid. Mine seems to have worked itself out so I didn't try anything out.

laurla's review against another edition

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-i appreciated all the explanations of how the thyroid works, and all its various parts and interactions. but i think the 'myers way' diet is ridiculous. you're prohibited everything except some meats, fruits, and veggies. this book also covers hyperthyroid, but as that isnt my problem i skipped that.
--TSH (thyroid stimulating hormone): the hormone released by your pituitary to stimulate your thyroid to produce thyroid hormone.
--T4: the storage form of thyroid hormone
--Free T4: the storage form of thyroid left free rather than bound
--T3: the active form of thyroid hormone
--Free T3: the active form of thyroid left free rather than bound
--TBG (thyroxine binding globulin): the protein that binds thyroid hormone so that the hormone can move through your bloodstream
--Reverse T3: a type of thyroid hormone that prevents free T3 from attaching to your cells, thereby blunting or preventing its effects
--Thyroid resistance: a disorder wherein your cells have difficulty receiving free T3, so even when blood levels of free T3 are optimal, not all of the hormone is able to enter your cells
--Thyroid antibodies (thyroid peroxidase [TPOAb] and thyroglobulin antibody [TgAb]): biochemicals produced by your immune system to attack your thyroid.
-what all these stories have in common: a doctor who is failing to effectively diagnose and treat thyroid dysfunction. how dismissive and unhelpful doctors have been. how they insist the real problem is depression or diminishing sex hormones, or stress, or anxiety, or 'all in your head'. conventional doctors dont run enough tests. they dont interpret the tests properly. they dont offer enough treatment options.
-thyroid is absolutely critical to every single cell in your body. every cell has a receptor for thyroid hormone, which means that no cell can function without it. and its not enough to have 'some' thyroid hormone. every cell needs exactly the right amount. you thought goldilocks was fussy? she's nothing compared to how frantic your cells get without optimal amounts of thyroid hormone.
-not only your thyroid is involved. the thyroid gland is at the center of a complex network of communication that involves your hypothalamus, pituitary, thyroid, and every single one of your cells. this network is called the thyroid signaling system and its detailed and intricate. interacts with all your other hormones.
-"these symptoms are making my life unlivable. i cant perform. i cant cope. i wanted my doctor to work with me and he just brushed me off. as if i was supposed to adjust to fit the treatment instead of him adjusting the treatment to fit me."
-when your body has too much estrogen, it makes more of a protein called thyroxine-binding globulin or TBG. too much TBG means too much of your thyroid hormone is bound, and not enough of it is free to enter your cells.
-the goal is not to eliminate stress, but to RELIEVE it.
- conventional doctors look for 'normal' reference ranges, which are very wide. i look for 'optimal' ranges, which are much narrower.
-"my doctor made me feel like i was just a complaining woman. like i was being fussy or difficult. even though i KNEW something was wrong, he wouldnt listen to me. he just looked at the labs. i'm a competent professional person, but he treated me like some silly schoolgirl who couldnt understand science."
-thyroid dysfunction is seven times more common among women than men. but men do have thyroid dysfunction too.
-check thyroid antibodies (they attack you and your thyroid)- thyroid peroxidase (TPO) and thyroglobulin antibody (TgAb). they indicate autoimmune dysfunction.
-thyroid wins 'most important yet most underappreciated award'.
-thyroid produces four types of thyroid hormones, two of which convert into still other types of hormones.
-when the thyroid feels TSH, it pulls iodine and tyrosine (amino acid) from your bloodstream and produces thyroid hormones. it converts the tyrosine into thyroglobulin and then attaches it to either one, two, three, or four iodine atoms creating T1, T2, T3, and T4.
-we dont know what T1 or T2 do.
-T4, thyroglobulin plus four iodine atoms, is the primary output of the thryoid gland. this is the storage form, circulating thru the bloodstream and stored in tissues. T4 doesnt enter your cells.
-T3 is the active form of the hormone. it has two sources. some is created and released by the thyroid itself. some is converted from T4. think of T4 as money in the bank, and T3 as cash in hand. you've always got cash in hand, but never more than you need. all the extra cash is kept in the bank. if you have too little T3, you're hypothyroid. too much T3, hyperthyroid.
-T4 is converted to T3 LOCALLY, by whatever part of the body needs more thyroid: the gut, liver, muscle, brain, and thyroid. your body's need for thyroid hormone is urgent, specific, and ever-changing.
-T4 is converted to T3 by an enzyme called deiodinase. this enzyme needs selenium, zinc, and iron to function properly. it strips one of the outside iodine atoms off the T4, turning it into free T3.
-reverse T3 is made when one of the inside hormone atoms is stripped away from T4 rather than one of the outside iodine atoms. like T4, reverse T3 is inactive. but it attaches to receptors in the cells where free T3 would normally lodge. and if the reverse T3 is taking up a receptor, it leaves less room for free T3. these things stimulate the body to make reverse T3: heavy metals, overexercise, starvation diets or low calorie weight loss plans that make the body think its starving and thus mobilizes all its resources to retain fat and avoid expending energy, and stress (mental, physical, emotional).
-T3 and T4 blood tests dont indicate how much is free and how much is bound and unavailable. TBG binds to T4 and T3, making them unavailable to your cells and tissues. 99% of the thyroid hormone in your bloodstream is bound. when the body makes too much TBG, too much hormone is bound and you get hypothyroid. too little, and and you get hyperthyroid.
-TBG levels are affected by estrogen levels and corticosteroid levels.
--your pituitary can release the wrong amount of TSH
--you can have too much TBG in your bloodstream, so too much T4 and T3 are bound and not enough is free
--your thyroid can release the wrong amount of T3
--your thyroid can release the wrong amount of T4
--your body can have difficulties converting T4 to T3, creating a shortage of active free T3
--your cells can have difficulties receiving T3, so even if they are getting enough hormone, they arent using it properly
--your body might be converting too much T4 into reverse T3, so the excess reverse T3 is blocking the effectiveness of free T3.
-if your stress never goes away and never gets relieved, your adrenals go into overdrive, continuously flooding your body with cortisol until they can no longer keep up with the constant demand. now you're in a state of adrenal dysfunction where your poor overworked adrenals are no longer able to produce enough stress hormones or where they are producing the wrong types of hormones at the wrong time. in a healthy body, you get a burst of cortisol in the morning which wakes you up. then cortisol levels taper off through the day and in the evening are so low you can drift off to sleep. when your adrenals are out of balance, your body suffers, and so does your thyroid.
-when stress levels are too high, the hypothalamus and pituitary slow down to not trigger any more cortisol, and slows down thyroid production.
-stress hormones affect the enzymes that convert T4 to T3, so under stress, more of our thyroid hormone remains in storage and less is available to power our cells.
-when stress is high the body converts more T3 into reverse T3, slowing the metabolism further.
-the stress response triggers inflammatory immune cells called cytokines, which make the thyroid receptors less sensitive to thyroid hormones, meaning you need more thyroid hormone to have the same effect. thyroid resistance. another way that lab results can be tricky to interpret. you can have the right amount of thyroid hormone in your bloodstream, but the cells are still being deprived.
-stress can cause excess estrogen to accumulate. which increases TBG, which attaches to you thyroid hormones and makes them inactive.
-hashimoto's thyroiditis is hypothyroid where the immune system attacks the thyroid. many doctors say the autoimmune factor doesnt matter. but no effort to stop the immune system's attacks on the thyroid means the immune system is left to continue its assault, leaving the thyroid requiring higher and higher levels of synthetic hormone to compensate for an increasingly damaged thyroid.
-to describe chronic inflammation: picture the members of a security squad trying to defend against a host of invaders: infections, toxins, stressors, harmful bacteria, and more. these invaders continue to assault the building the security squad/immune system is defending, so that they never have a moment to take a break, even for a meal or a good nights sleep. at first they're selective about whom they fire at, because the inflammatory response is a powerful one that can destroy good guys as well as bad. but when the threats just keep coming, the poor beleaguered security squad begins to lose control. their carefully targeted shooting becomes random and desperate, destroying bad and good and causing a huge amount of destruction. if the attacks ON your immune system keep coming, the attacks FROM your immune system keep coming as your poor beleaguered immune system begins attacking you.
-80% of your immune system is located in the gut, given that the vast majority of threats to your system come in through what you eat or drink).
-thyroid antibodies (TPO and TgAb) target your thyroid, and there are lab tests for them.
-in molecular mimicry, the autoimmune response confuses the bodys own tissue with some foreign invader. the common thyroid doppelganger is the protein gluten. casein, a protein found in dairy products, occasionally gets mistaken for thyroid as well.
-gluten shows up in a lot of personal care products, so even when you're not eating it, you still may be rubbing it on your skin.
-cortisol weakens your immune system's primary barriers, the blood-brain barrier, lungs, and gut barrier, releasing gluten and casein into the bloodstream.
-many industrial chemicals act just like estrogen, called xenoestrogens. too much exposure to these toxins has the same effect as giving your body a massive overdose of estrogen. excess estrogen promotes TBG which leads to too much BOUND rather than FREE thyroid hormone.
-testing only the TSH tells you ONLY whats going on between the pituitary and the thyroid.
-when doctors and laboratories developed the standard reference ranges for thyroid readings, they used readings taken from people with THYROID DYSFUNCTION! they didnt use healthy people. so right from the start those numbers and ranges were out of whack.
-these standards were updated in 2003 from 0.5 to 5.0 range to 0.3 to 3.0 range. the author considers this range still too wide. [most people with hypothyroid feel best in the 1.0 range, myself included. it makes a HUGE difference, that little bit of number change]. and many doctors still use the old range despite it being 13 years.
-it takes an average of 18 YEARS for research to make its way into standard medical practice.
--optimal lab values according to the author:
--TSH 1.0 to 2.0 uIU/mL
--FT4 > 1.1 ng/dL
--FT3 > 3.2 pg/mL
--RT3 < than a 10:1 ration of RT3 to FT3
--Thyroid peroxidase antibodies < 9 IU/mL or negative
--Thyroglobulin antibodies < 4 IU/mL or negative.
-additional lab work needed for optimal thyroid function:
--iron/ferritin (serum): normal 12-150 ng/mL; optimal 75-100 ng/mL
--vitamin D (serum): normal 30-100 ng/mL; optimal 50-70 ng/mL
--vitamin A (serum): normal 0.20-1.20 mg/L; optimal 0.8-1 mg/L
--homocysteine (syrum): normal 4-15 mmol/L; optimal 7-8 mmol/L
--selenium (RBC): 120-300 mcg/L; optimal 200-250 mcg/L
--zinc (RBC): normal 790-1500 mcg/dL; optimal 1000-1200 mcg/dL
--magnesium (RBC): normal 1.5-3.1 mmol/L; optimal 2.5-3.0 mmol/L
-syhnthroid is now our countries most prescribed drug, with 21.5 million prescriptions each year.
-"the doctor suggested exercise might help, but how can i exercise if i'm too tired to even move?"
-the authors myers way diet has you avoiding all grains and legumes because they promote leaky gut. the edible portion of these plants is the seed, which contains the embryo. in order to protect this embryo, a plant produces its own natural insecticides to repel pests. the chemicals help the seeds pass undigested through an animals system so that when they are expelled with the animals feces, they remain intact and can produce more plants. the chemicals that enable the see's survival under those circumstances can be very damaging to those of you with an autoimmune disease.
-grains and legumes also contain lectins, plant proteins that bind to carbohydrates. two types of lectins are especially challenging: agglutinins and prolamins.
-agglutinins are another type of natural insecticide that can aggravate autoimmune disease. GMO's have been specially engineered to produce even MOE of their natural insecticides.
-prolamins are hard to digest. gluten is a type of prolamin, and even gluten-free grains contain a prolamin similar in structure to gluten. they can cause an immune response in anyone who is sensitive to gluten.
-grains also contain phyates and phytic acid, which inhibit digestio and bind to zinc, iron, and calcium, preventing their absorption. these minerals are crucial for both thyroid and immune function. GMO grians contain an even greater concentration of phytic acid.
-psuedograins and legumes contain saponins, or glycoalkaloids, another natural insecticide produced by the plants. they can pass into your bloodstream and destroy red blood cells.
-dairy's casein can trigger molecular mimicry and is then highly inflammatory. much dairy also contains antibiotics, bovine growth hormone, and unfriendly bacteria due to the crowded poor conditions in which the animals are raised.
-nightshades are high in lectins.
-the burden of proof on corporations is NOT to show that each new industrial chemical is safe. in order to get the EPA or FDA to issue a regulation on industrial chemicals, someone has to show that a particular chemical is UNSAFE.
-as a way to destress - binaural beats. when your brain receives two different frequencies - one in each ear, it creates a third frequency in an effort to syncronize them. this third frequency can be used to guide your mind into a more relaxed state that helpts you disconnect from anxiety and enables you to relax and feel more positive. many different types of binaural beats albums.
-calcium can interfere with the absorption of supplemental thyroid hormone
-her myers way multivitamin complete, requires three pills with lunch, and three pills with dinner!
-the author incorrectly confuses the fluoride in toothpaste with the fluoride in water. she says there is no benefit to the teeth, no proof of cavity/decay prevention with fluoride. that is incorrect. it is PROVEN with many many studies over many years, that fluoride in toothpaste applied to the teeth and not consumed, absolutely DOES prevent tooth decay and helps tooth enamel. however, fluoride added to the water and consumed, does NOT prevent tooth decay or help tooth enamel. there is a difference. and its why toothpaste for toddlers who might swallow it, is fluoride free. you dont want it in your water. you do want it in your toothpaste.
-she recommends 500-1000 mg a day of magnesium, without warning people that it's a stool softener and in high doses like that can cause diarrhea.

mpevans0517's review against another edition

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5.0

I read up to the point where the 28 day plan begins. I'm not sure if I'll be doing the plan, but the information in this book was so informative and interesting it kept me engaged, and for a non-fiction book about thyroids to do that... is impressive. Thoroughly enjoyed what I need to be cutting out, adding in, things that affect my thyroid that I never would have realized.

iamshelleyleigh's review against another edition

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5.0

Dr. Myers helped me to finally understand the true breadth of my Hashimoto's autoimmune disease. I feel entirely equipped to handle the future of my health, from doctors to self-care. Having this book as a resource to come back to is so comforting.

I was worried that the book would be to "meaty" or scientific for me to really understand, but Dr. Myers does an amazing job explaining all of the science in a way that's not only easy to understand, but also retain. She paints a very clear picture without sending you too far into the weeds.

I'll be forever grateful for Dr. Myers and all of her work. Can't recommend this one enough for anyone dealing with thyroid issues.